Non-culture-based analysis of bacterial populations from patients with chronic rhinosinusitis.

نویسندگان

  • Daniel A Power
  • Jeremy P Burton
  • Chris N Chilcott
  • John R Tagg
  • Patrick J Dawes
چکیده

Middle meatus aspirates from patients with chronic rhinosinusitis were analyzed by bacterial culture, denaturing gradient gel electrophoresis (DGGE), and antibiotic sensitivity techniques. DGGE detected a greater bacterial diversity than culture methods. Although resistance to antibiotics was low, there was evidence of changes in the composition of the bacterial microbiota over time, and the presence of noncultured bacteria was demonstrated.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 43 11  شماره 

صفحات  -

تاریخ انتشار 2005